Metoprolol USP Related Compound B - Names and Identifiers
Metoprolol USP Related Compound B - Physico-chemical Properties
Molecular Formula | C12H17ClO3
|
Molar Mass | 244.71 |
Density | 1.157±0.06 g/cm3(Predicted) |
Boling Point | 364.5±32.0 °C(Predicted) |
Solubility | Chloroform (Slightly), Methanol (Slightly) |
Appearance | neat |
Color | Colourless |
BRN | 7622429 |
pKa | 13.12±0.20(Predicted) |
Storage Condition | Refrigerator, under inert atmosphere |
Metoprolol USP Related Compound B - Risk and Safety
Hazard Symbols | Xn - Harmful
|
Risk Codes | 22 - Harmful if swallowed
|
HS Code | 2909490000 |
Metoprolol USP Related Compound B - Introduction
rac 1-Chloro-3-[4-(2-methoxy ethyl) phenyl]-2-propanol is a chemical substance with the chemical name rac 1-Chloro-3-[4-(2-methoxyethyl)phenoxy]-2-propanol. Its molecular formula is C13H19ClO3, the relative molecular mass is 260.74. The following is a description of the properties, uses, preparation and safety information of rac 1-Chloro-3-[4-(2-methoxy ethyl)phenoxy]-2-propanol:
Nature:
rac 1-Chloro-3-[4-(2-methoxyethyl)phenoxy]-2-propanol is a white solid or powdery substance. It is soluble in ether, alcohol and chloroform, slightly soluble in water and ether, and practically insoluble in petroleum ether.
Use:
rac 1-choro-3-[4-(2-methoxy ethyl)phenoxy]-2-propanol is a highly effective beta-blocker commonly used to treat cardiovascular diseases such as hypertension and angina. It can reduce blood pressure and reduce the burden on the heart by blocking beta receptors to slow down the heart rate and reduce the heart's contractility.
Method:
The synthesis of rac 1-chroo-3-[4-(2-methoxyethyl)phenoxy]-2-propanol is usually carried out by the following steps:
1.2-methoxyethyl benzene is reacted with bromopropanol to obtain 2-methoxyethyl propanol.
2. Reaction of 2-methoxyethyl propanol with hydrogen chloride yields 1-chloro-3-[4-(2-methoxyethyl)phenoxy]-2-propanol, rac 1-chlorophyll -3-[4-(2-methoxy) phenyl]-2-propanol.
Safety Information:
rac 1-choro-3-[4-(2-methoxyethyl)phenoxy]-2-propanol is a chemical, so you need to pay attention to its safety during use. Some security measures include:
1. Avoid skin contact and inhalation of the substance, wear protective gloves and masks, and operate in a well-ventilated place.
2. In case of contact with skin or eyes, rinse immediately with water and seek medical help.
3. Storage should be away from the fire and flammable materials, stored in a dry, ventilated place.
4. In the use or disposal of the substance, should follow the relevant safety procedures and environmental regulations.
The above is only a general introduction. The specific use and operation of the chemical substance should refer to the relevant safety technical documents and follow the relevant regulations and guidelines.
Last Update:2024-04-10 22:29:15